Healing Support for Cancer: IP6 (Inositol Hexaphosphate)
What exactly is IP6?
Inositol hexaphosphate (IP6) is a sugar, actually very much like glucose, that is found in rice, beans, corn, sesame seeds, wheat bran, and other high-fiber foods. Unfortunately IP6 it is only readily absorbed from these dietary sources if the body has adequate amounts of digestive enzymes to break it down, which many of us are lacking. Given this, IP6 in supplement or bulk form may be the best option for cancer patients or those wishing to take advantage of its cancer-protective effects.
What it does.
IP6, first and foremost, is believed to be an antioxidant, preventing damage to the cells. What makes it even more powerful though, is its capability to activate NK (Natural Killer) cells and prevent abnormal, cancer-promoting signals from reaching the cell’s nucleus. There’s more: research shows that IP6 slows abnormal cell division, may convert tumor cells back into normal cells, supports programmed cell death, and inhibits the formation of tumor-feeding blood vessels. Finally, this compound has proven to boost the effectiveness of certain chemotherapy and hormone drugs.
I’m a big proponent of IP6 because the positive research findings are clear. For instance, IP6 has been effective against every type of cancer cell tested (Shamsuddin et al. 1997; Grases et al. 2002). And when studying cancer in lab animals in 1989, Shamsuddin et al. found that oral administration of IP6 or injection of IP6 at the site of the tumor resulted in tumors 1/3 the size of the controls, increasing survival rate.
So we’ve covered some of the pros of IP6, but what about the cons? Well, that’s the thing. The negative side effects of this compound are minimal and can be prevented. For instance, IP6 increases risk of bleeding when used with other blood-thinning drugs or supplements so it should not be taken with those. It also reduces the absorption of several minerals including iron, magnesium, calcium and zinc, so if you decide to take IP6 regularly, look into a quality multi-mineral supplement to take simultaneously. Amazingly, toxicity studies dating all the way back to the 1950s show that the only side effects from a daily dose of 9 grams over a 3-year-period were quite positive – decreased occurrence of kidney stones, improvement of fatty liver, and lowered cholesterol levels. You can’t beat that!
References and Studies:
- IP6 and Protection against cancer http://www.ncbi.nlm.nih.gov/pubmed/17044765
- IP6 vs Liver Cancer http://www.ncbi.nlm.nih.gov/pubmed/9891449
- IP6 vs Pancreatic Cancer http://www.ncbi.nlm.nih.gov/pubmed/15919420
- IP6 vs Breast Cancer http://www.ncbi.nlm.nih.gov/pubmed/15868430
- IP6 vs Breast Cancer http://www.ncbi.nlm.nih.gov/pubmed/12846414
- IP6 and Chemotherapy http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829500/
- IP6 vs Skin Cancer http://www.ncbi.nlm.nih.gov/pubmed/10625952
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